Like Menopur? Thank a Nun!

As with many breakthrough fertility medication discoveries, it often happens by chance, luck or divine intervention. In the case of Menopur, considering the first essential components were donated by postmenopausal nuns, divine intervention seems apt.

Menopur, often used as an IVF medication, and its discovery is one among many odd medicinal wonders. Consider that Alexander Fleming discovered penicillin after leaving bread out in his less-than-hygienic lab. Or did you know that Viagra was first developed as a hypertension treatment for high blood pressure?  Of course, it had other uses, they discovered.

Menopur: A Holy Cause

Menopur was developed in the 1940s by a scientist, named Donini, whose goal was to help repopulate Europe after World War II. The company he worked for had developed the ability to purify and extract luteinizing hormone (LH) and follicle stimulating hormone (FSH) by using urine from already pregnant women. However, he found that postmenopausal women had super high concentrations of the hormones.

When in menopause a woman’s body produces these hormones in excessive quantities trying to stimulate the ovaries into producing more eggs (even if there are no more to produce). The question for Donini became: Where do I get a large quantity of urine from women who are menopausal to continue to develop the medication? Enter, the nuns. When told about the holy cause of helping women to have children, 400 volunteered. From all across Italy’s Catholic retirement homes came tankers of donated urine.

Menopur Successfully Treats Infertility

Decades of testing finally produced a viable and stable menopur injectable that resulted in the first birth in 1962. Over the next two years there would be 20 more menopur success stories. Flash forward to the 1980s and the demand for “the special ingredient” had risen so significantly, the company knew they needed to synthesize the hormones. The resulting drug is today called Gonal-F and was approved for use in 1995.

Menopur Fertility Injections

Today, you can still get menopur to assist and support your body’s reproductive health. It is most often sold as a vial with powder in it. In the package there is often a separate vial with purified water. You take a certain amount of the water, inject it into the vial with the powder, shake it up to mix, and then inject the mixture. Menopur is often prescribed for women who have PCOS and who need both the FSH and LH hormones for egg production.

Personal Experiences with Menopur

Reddit/Infertility Forum

Patient #1: She is having difficulty with giving herself the Menopur shots and asks others for tips for giving herself the fertility drug shot. One poster stated she had the nurse take a sharpie and draw a circle so she could remember where the best injection site is (then continued to touch them up). Another said she found out the hard way that leaving even a small bit of Menopur on the end of the needle before injecting can make it burn worse. She recommends Patient #1 wipe the needle off with a sterile swab, then air dry before injecting.

Patient #2: On a different thread, same Menopur topic, this patient writes of her concern about the use of urine to create the IVF drug. Others quickly respond that it is made almost completely synthetically these days, but many say it would not matter because desperate times call for desperate measures.

Whatoexpect.com

Patient #1: A 40 year old woman asks others on the forum about Menopur and what she should expect. A 43 year old woman responds quickly and states that it most definitely helped her produce a good amount of eggs. She’s hopeful while in her 2ww. A 38 year old respondent reports she used Menopur and now has a happy healthy little girl.

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